Sandrine Pierson
Latest publications
The tumor microenvironment-dependent transcription factors AHR and HIF-1α are dispensable for leukemogenesis in the Eµ-TCL1 mouse model of chronic lymphocytic leukemia.
- Tumor Stroma Interactions
2021 Sep. Cancers.13(18):4518.
Purification of leukemia-derived exosomes to study microenvironment modulation.
- Tumor Stroma Interactions
- Platform National Cytometry
2019 Jan. Methods Mol Biol.1884:231-245.
Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Platform National Cytometry
- Tumor Immunotherapy and Microenvironment
- NORLUX Neuro-Oncology Laboratory
- Allergy and Clinical Immunology
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.
- Tumor Stroma Interactions
2018 Apr. Haematologica.103(4):e154-e157. Epub 2018 Jan 5.
Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Platform National Cytometry
- NORLUX Neuro-Oncology Laboratory
2014 Aug. Leukemia.28(8):1636-46. Epub 2014 Jan 14.
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
2011 Sep. Cancer Res.71(18):5976-86. Epub 2011 Aug 2.
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2011 Apr. Proc Natl Acad Sci U S A.108(16):6573-8. Epub 2011 Apr 1.
The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform National Cytometry
2010 Apr. Mol Cancer Ther.9(5):1349-60. Epub 2010 Apr 20.