Latest publications

[Impact of small extracellular vesicles on anti-tumor immunity in chronic lymphocytic leukemia in vivo]. (Doctoral thesis)

  • Tumor Stroma Interactions
November 27, 2021
2021 Nov. Paris: University Paris-Saclay, 2021. 247 p.
By:
  • Gargiulo E.
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The tumor microenvironment-dependent transcription factors AHR and HIF-1α are dispensable for leukemogenesis in the Eµ-TCL1 mouse model of chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
September 08, 2021
2021 Sep. Cancers.13(18):4518.
By:
  • Gonder S
  • Largeot A
  • Gargiulo E
  • Pierson S
  • Fernandez Botana I
  • Pagano G
  • Paggetti J
  • Moussay E.
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In vitro sensitivity to venetoclax and microenvironment protection in hairy cell leukemia.

  • Tumor Stroma Interactions
July 26, 2021
2021 Jul. Front Oncol.11:598319.
By:
  • Vereertbrugghen A
  • Colado A
  • Gargiulo E
  • Bezares RF
  • Fernandez Grecco H
  • Cordini G
  • Custidiano MDR
  • Francois JH
  • Berchem G
  • Borge M
  • Paggetti J
  • Moussay E
  • Gamberale R
  • Giordano M
  • Morande PE.
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Immunomodulatory effects of different intravenous immunoglobulin preparations in chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
June 21, 2021
2021 Jun. Sci Rep.11(1):12926.
By:
  • Colado A
  • Elias EE
  • Sarapura Martinez VJ
  • Cordini G
  • Morande P
  • Bezares F
  • Giordano M
  • Gamberale R
  • Borge M.
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Intrinsic resistance of chronic lymphocytic leukemia cells to NK cell- mediated lysis can be overcome in vitro by pharmacological inhibition of Cdc42-induced actin cytoskeleton remodeling.

  • Cytoskeleton and Cancer Progression
  • Tumor Stroma Interactions
May 24, 2021
2021 May. Front Immunol.12:619069.
By:
  • Wurzer H
  • Filali L
  • Hoffmann C
  • Krecke M
  • Biolato AM
  • Mastio J
  • De Wilde S
  • Francois JH
  • Largeot A
  • Berchem G
  • Paggetti J
  • Moussay E
  • Thomas C.
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AID overexpression leads to aggressive murine CLL and nonimmunoglobulin mutations that mirror human neoplasms.

  • Tumor Stroma Interactions
March 02, 2021
2021 Mar. Blood.138(3):246-258.
By:
  • Morande PE
  • Yan XJ
  • Sepulveda J
  • Seija N
  • Marquez ME
  • Sotelo N
  • Abreu C
  • Crispo M
  • Fernandez-Grana G
  • Rego N
  • Bois T
  • Methot SP
  • Palacios F
  • Remedi V
  • Rai KR
  • Buschiazzo A
  • Di Noia JM
  • Navarrete MA
  • Chiorazzi N
  • Oppezzo P.
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Method for the analysis of the tumor microenvironment by mass cytometry: Application to chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
October 20, 2020
2020 Oct. Front Immunol.11:578176.
By:
  • Gonder S
  • Fernandez Botana I
  • Wierz M
  • Pagano G
  • Gargiulo E
  • Cosma A
  • Moussay E
  • Paggetti J
  • Largeot A.
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Diagnostic and therapeutic potential of extracellular vesicles in B-cell malignancies.

  • Tumor Stroma Interactions
September 29, 2020
2020 Sep. Front Oncol.10(2057):580874.
By:
  • Gargiulo E
  • Morande PE
  • Largeot A
  • Moussay E
  • Paggetti J.
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Characterisation of the tumour microenvironment in chronic lymphocytic leukemia by mass cytometry: implications for immunotherapy. (Doctoral thesis)

  • Tumor Stroma Interactions
September 14, 2020
2020 Sep. Paris: University Paris-Saclay, 2020. 271 p.
By:
  • Wierz M.
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Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes.

  • Cytoskeleton and Cancer Progression
  • Tumor Stroma Interactions
September 09, 2020
2020 Sep. Int Rev Cell Mol Biol.356:99-130. Epub 2020 Sep 9.
By:
  • Biolato AM
  • Filali L
  • Wurzer H
  • Hoffmann C
  • Gargiulo E
  • Valitutti S
  • Thomas C.
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Hematological malignancy-derived small extracellular vesicles and tumor microenvironment: The art of turning foes into friends.

  • Tumor Stroma Interactions
May 27, 2019
2019 May. Cells.8(5):pii: E511.
By:
  • Gargiulo E
  • Paggetti J
  • Moussay E.
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The B-side of cancer immunity: The underrated tune.

  • Tumor Stroma Interactions
May 13, 2019
2019 May. Cells.8(5):pii: E449.
By:
  • Largeot A
  • Pagano G
  • Gonder S
  • Moussay E
  • Paggetti J.
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HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells.

  • Tumor Stroma Interactions
April 01, 2019
2019 Apr. Oncogene.38(15):2767-2777. Epub 2018 Dec 12.
By:
  • Causse SZ
  • Marcion G
  • Chanteloup G
  • Uyanik B
  • Boudesco C
  • Grigorash BB
  • Douhard R
  • Dias AMM
  • Dumetier B
  • Dondaine L
  • Gozzi GJ
  • Moussay E
  • Paggetti J
  • Mirjolet C
  • de Thonel A
  • Dubrez L
  • Demidov ON
  • Gobbo J
  • Garrido C.
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Purification of leukemia-derived exosomes to study microenvironment modulation.

  • Tumor Stroma Interactions
  • Platform National Cytometry
January 01, 2019
2019 Jan. Methods Mol Biol.1884:231-245.
By:
  • Wierz M
  • Pierson S
  • Gargiulo E
  • Guerin C
  • Moussay E
  • Paggetti J.
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Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis.

  • Tumor Stroma Interactions
October 01, 2018
2018 Oct. Biochim Biophys Acta Mol Basis Dis.1864(10):3099-3108. Epub 2018 May 30.
By:
  • Dehghani Amirabad A
  • Ramasamy P
  • Wierz M
  • Nordstrom K
  • Kessler SM
  • Schulz MH
  • Simon M.
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High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Tumor Immunotherapy and Microenvironment
May 24, 2018
2018 May. OncoImmunology.7(8):e1465167.
By:
  • Wierz M
  • Janji B
  • Berchem G
  • Moussay E
  • Paggetti J.
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Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
April 25, 2018
2018 Apr. OncoImmunology.7(8):e1452583.
By:
  • Noman MZ
  • Paggetti J
  • Moussay E
  • Berchem G
  • Janji B.
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Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

  • Tumor Stroma Interactions
  • Platform National Cytometry
  • Tumor Immunotherapy and Microenvironment
  • NORLUX Neuro-Oncology Laboratory
  • Allergy and Clinical Immunology
April 05, 2018
2018 Apr. Blood.131(14):1617-1621. Epub 2018 Feb 13.
By:
  • Wierz M
  • Pierson S
  • Guyonnet L
  • Viry E
  • Lequeux A
  • Oudin A
  • Niclou SP
  • Ollert M
  • Berchem G
  • Janji B
  • Guerin C
  • Paggetti J
  • Moussay E.
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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.

  • Tumor Stroma Interactions
April 01, 2018
2018 Apr. Haematologica.103(4):e154-e157. Epub 2018 Jan 5.
By:
  • Wierz M
  • Pierson S
  • Chouha N
  • Desaubry L
  • Francois JH
  • Berchem G
  • Paggetti J
  • Moussay E.
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Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

  • Tumor Immunotherapy and Microenvironment
  • Tumor Stroma Interactions
  • Platform National Cytometry
October 31, 2017
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
By:
  • Mgrditchian T
  • Arakelian T
  • Paggetti J
  • Noman MZ
  • Viry E
  • Moussay E
  • Van Moer K
  • Kreis S
  • Guerin C
  • Buart S
  • Robert C
  • Borg C
  • Vielh P
  • Chouaib S
  • Berchem G
  • Janji B.
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