Kris Van Moer
Latest publications
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy.
- Tumor Immunotherapy and Microenvironment
2021 Jul. Oncogene.40(28):4725-4735. Epub 2021 Jun 21.
Epithelial to mesenchymal transition regulates surface PD-L1 via CMTM6 and CMTM7 induction in breast cancer.
- Tumor Immunotherapy and Microenvironment
2021 Mar. Cancers.13(5):1165.
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy.
- Tumor Immunotherapy and Microenvironment
2020 May. Sci Adv.6(18):eaax7881.
Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints.
- Tumor Immunotherapy and Microenvironment
2019 Aug. Cancer Lett.458:13-20. Epub 2019 May 25.
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.
- Tumor Immunotherapy and Microenvironment
- Computational Biomedicine
2018 Feb. OncoImmunology.7(4):e1345415.
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
- Platform National Cytometry
2017 Oct. Proc Natl Acad Sci U S A.114(44):E9271-E9279. Epub 2017 Oct 16.
The critical role of hypoxia in tumor-mediated immunosuppression. In Hypoxia and Human Diseases. (Book Chapter)
- Tumor Immunotherapy and Microenvironment
2017 Feb. Zheng J, ed. Intech, 2017. p.349-364. ISBN 978-953-51-2895-3.
Autophagy regulation of the tumor immunity: An old housekeeper for a new function. In Cell Death - Autophagy, Necrosis and Apoptosis. (Book Chapter)
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
2015 Dec. Ntuli DT, ed. Rijeka: InTech, 2015. p.37-61. ISBN 978-953-51-2236-4.
The selective degradation of synaptic connexin 43 protein by hypoxia-induced autophagy impairs natural killer cell-mediated tumor cell killing.
- Tumor Immunotherapy and Microenvironment
2015 Sep. J Biol Chem.290(39):23670-9. Epub 2015 Jul 28.
Bronchial airway gene expression in smokers with lung or head and neck cancer.
- NORLUX Neuro-Oncology Laboratory
- Platform LUXGEN - Micro-Array
- Tumor Immunotherapy and Microenvironment
2014 Apr. Cancer Med.3(2):322-36. Epub 2014 Feb 4.
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia.
- Tumor Immunotherapy and Microenvironment
- NORLUX Neuro-Oncology Laboratory
2013 Oct. Proc Natl Acad Sci U S A.110(43):17450-5. Epub 2013 Oct 7.
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
2011 Sep. Cancer Res.71(18):5976-86. Epub 2011 Aug 2.
The acquisition of resistance to TNFalpha in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2011 Jul. Autophagy.7(7):760-70. Epub 2011 Jul 1.
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2011 Apr. Proc Natl Acad Sci U S A.108(16):6573-8. Epub 2011 Apr 1.
Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform LUXGEN - Micro-Array
2010 May. Mol Cancer.9(1):115. emoussay, vpalissot, lvallar, $, $, velkhoury, naouali, kvanmoer, bleners, fbernardin, .amuller, $, $, $, $, evandyck, gberchem.
The histone deacetylase inhibitor MGCD0103 induces apoptosis in B-cell chronic lymphocytic leukemia cells through a mitochondria-mediated caspase activation cascade.
- Tumor Stroma Interactions
- Tumor Immunotherapy and Microenvironment
- Platform National Cytometry
2010 Apr. Mol Cancer Ther.9(5):1349-60. Epub 2010 Apr 20.