Latest publications

Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid.

  • Personalized Therapy Discovery
  • Disease Modeling & Screening Platform
  • Luxembourg Center of Neuropathology
December 06, 2021
2021 Dec. Cancer Biol Ther. accepted.
By:
  • Kim H
  • El-Khoury V
  • Schulted N
  • Zhand T
  • Betged J
  • Cousina L
  • Fellif E
  • Pessauxf P
  • Ogiera A
  • Opitzi O
  • Kuj B
  • Ebertd MP
  • Kwon Y-J.

Personalized drug screening for functional tumor profiling. In Elements in Molecular Oncology. (Book Chapter)

  • Luxembourg Center of Neuropathology
  • Disease Modeling & Screening Platform
  • Personalized Therapy Discovery
November 15, 2021
2021 Nov. Cambridge, 2021. Accepted
By:
  • El-Khoury V
  • Michel T
  • Kim H
  • Kwon Y-J.

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function.

  • Transversal Translational Medicine
  • Disease Modeling & Screening Platform
  • NORLUX Neuro-Oncology Laboratory
  • Personalized Therapy Discovery
November 09, 2021
2021 Nov. Sci Rep.11(1):21946.
By:
  • Barbuti PA
  • Ohnmacht J
  • Santos BFR
  • Antony PM
  • Massart F
  • Cruciani G
  • Dording CM
  • Pavelka L
  • Casadei N
  • Kwon YJ
  • Kruger R.

CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6.

  • Immuno-Pharmacology and Interactomics
  • Tumor Immunotherapy and Microenvironment
  • Allergy and Clinical Immunology
  • Personalized Therapy Discovery
March 02, 2021
2021 Mar. Cancers.13(5):1054.
By:
  • Chevigné A
  • Janji B
  • Meyrath M
  • Reynders N
  • D’Uonnolo G
  • Uchański T
  • Xiao M
  • Berchem G
  • Ollert M
  • Kwon Y-J
  • Noman MZ
  • Szpakowska M.

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Neuro-Immunology Group
  • Computational Biomedicine
  • Multiomics Data Science
  • Luxembourg Center of Neuropathology
  • Personalized Therapy Discovery
December 01, 2020
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
By:
  • Golebiewska A
  • Hau AC
  • Oudin A
  • Stieber D
  • Yabo YA
  • Baus V
  • Barthelemy V
  • Klein E
  • Bougnaud S
  • Keunen O
  • Wantz M
  • Michelucci A
  • Neirinckx V
  • Muller A
  • Kaoma T
  • Nazarov PV
  • Azuaje F
  • De Falco A
  • Flies B
  • Richart L
  • Poovathingal S
  • Arns T
  • Grzyb K
  • Mock A
  • Herold-Mende C
  • Steino A
  • Brown D
  • May P
  • Miletic H
  • Malta TM
  • Noushmehr H
  • Kwon YJ
  • Jahn W
  • Klink B
  • Tanner G
  • Stead LF
  • Mittelbronn M
  • Skupin A
  • Hertel F
  • Bjerkvig R
  • Niclou SP.

Identification of a blood-based protein biomarker panel for lung cancer detection.

  • Personalized Therapy Discovery
  • Competence Center for Methodology and Statistics
  • Multiomics Data Science
  • Quantitative Biology Unit
  • NORLUX Neuro-Oncology Laboratory
June 19, 2020
2020 Jun. Cancers.12(6):E1629.
By:
  • El-Khoury V
  • Schritz A
  • Kim SY
  • Lesur A
  • Sertamo K
  • Bernardin F
  • Petritis K
  • Pirrotte P
  • Selinsky C
  • Whiteaker JR
  • Zhang H
  • Kennedy JJ
  • Lin C
  • Lee LW
  • Yan P
  • Tran NL
  • Inge LJ
  • Chalabi K
  • Decker G
  • Bjerkvig R
  • Paulovich AG
  • Berchem G
  • Kim YJ.