Alessandro Michelucci

Latest publications

Special Issue "Microglia Heterogeneity and Its Relevance for Translational Research".

  • Neuro-Immunology Group
November 16, 2021
2021 Nov. Int J Mol Sci.22(22):12350.
By:
  • Michelucci A
  • Miron VE
  • Priller J.

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.

  • Neuro-Immunology Group
November 09, 2021
2021 Nov. Immunity.54(11):2531-2546 e5. Epub 2021 Oct 12.
By:
  • Faas M
  • Ipseiz N
  • Ackermann J
  • Culemann S
  • Gruneboom A
  • Schroder F
  • Rothe T
  • Scholtysek C
  • Eberhardt M
  • Bottcher M
  • Kirchner P
  • Stoll C
  • Ekici A
  • Fuchs M
  • Kunz M
  • Weigmann B
  • Wirtz S
  • Lang R
  • Hofmann J
  • Vera J
  • Voehringer D
  • Michelucci A
  • Mougiakakos D
  • Uderhardt S
  • Schett G
  • Kronke G.

Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain (COL4A6) as a novel regulator of striatal axonal branching in mice.

  • Neuro-Immunology Group
  • Luxembourg Center of Neuropathology
November 01, 2021
2021 Nov. Genes Brain Behav.20(8):e12769. Epub 2021 Sep 28.
By:
  • Thomas MH
  • Gui Y
  • Garcia P
  • Karout M
  • Gomez Ramos B
  • Jaeger C
  • Michelucci A
  • Gaigneaux A
  • Kollmus H
  • Centeno A
  • Schughart K
  • Balling R
  • Mittelbronn M
  • Nadeau JH
  • Sauter T
  • Williams RW
  • Sinkkonen L
  • Buttini M.

Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors.

  • NORLUX Neuro-Oncology Laboratory
  • Neuro-Immunology Group
  • Translational Radiomics
June 18, 2021
2021 Jun. STAR Protoc.2(2):100534.
By:
  • Oudin A
  • Baus V
  • Barthelemy V
  • Fabian C
  • Klein E
  • Dieterle M
  • Wantz M
  • Hau AC
  • Dording C
  • Bernard A
  • Michelucci A
  • Yabo YA
  • Kanli G
  • Keunen O
  • Bjerkvig R
  • Niclou SP
  • Golebiewska A.

NF-kappaB and TNF affect the astrocytic differentiation from neural stem cells.

  • Neuro-Immunology Group
April 08, 2021
2021 Apr. Cells.10(4):840.
By:
  • Birck C
  • Ginolhac A
  • Pavlou MAS
  • Michelucci A
  • Heuschling P
  • Grandbarbe L.

Microglia in health and disease: The strength to be diverse and reactive.

  • Neuro-Immunology Group
  • Luxembourg Center of Neuropathology
March 31, 2021
2021 Mar. Front Cell Neurosci.660523.
By:
  • Uriarte Huarte O
  • Richart L
  • Mittelbronn M
  • Michelucci A.

Single-cell transcriptomics and in situ morphological analyses reveal microglia heterogeneity across the nigrostriatal pathway.

  • Neuro-Immunology Group
  • Luxembourg Center of Neuropathology
March 11, 2021
2021 Mar. Front Immunol.12:639613.
By:
  • Uriarte Huarte O
  • Kyriakis D
  • Heurtaux T
  • Pires-Afonso Y
  • Grzyb K
  • Halder R
  • Buttini M
  • Skupin A
  • Mittelbronn M
  • Michelucci A.

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Neuro-Immunology Group
  • Computational Biomedicine
  • Multiomics Data Science
  • Luxembourg Center of Neuropathology
  • Personalized Therapy Discovery
December 01, 2020
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
By:
  • Golebiewska A
  • Hau AC
  • Oudin A
  • Stieber D
  • Yabo YA
  • Baus V
  • Barthelemy V
  • Klein E
  • Bougnaud S
  • Keunen O
  • Wantz M
  • Michelucci A
  • Neirinckx V
  • Muller A
  • Kaoma T
  • Nazarov PV
  • Azuaje F
  • De Falco A
  • Flies B
  • Richart L
  • Poovathingal S
  • Arns T
  • Grzyb K
  • Mock A
  • Herold-Mende C
  • Steino A
  • Brown D
  • May P
  • Miletic H
  • Malta TM
  • Noushmehr H
  • Kwon YJ
  • Jahn W
  • Klink B
  • Tanner G
  • Stead LF
  • Mittelbronn M
  • Skupin A
  • Hertel F
  • Bjerkvig R
  • Niclou SP.

Pituitary tumor transforming gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging.

  • Neuro-Immunology Group
  • Luxembourg Center of Neuropathology
September 23, 2020
2020 Sep. Front Genet.11(1119).
By:
  • Gui Y
  • Thomas MH
  • Garcia P
  • Karout M
  • Halder R
  • Michelucci A
  • Kollmus H
  • Zhou C
  • Melmed S
  • Schughart K
  • Balling R
  • Mittelbronn M
  • Nadeau JH
  • Williams RW
  • Sauter T
  • Buttini M
  • Sinkkonen L.

Revealing and harnessing tumour-associated microglia/macrophage heterogeneity in glioblastoma.

  • Neuro-Immunology Group
  • NORLUX Neuro-Oncology Laboratory
January 21, 2020
2020 Jan. Int J Mol Sci.21(3):E689.
By:
  • Pires-Afonso Y
  • Niclou SP
  • Michelucci A.