Dirk Brenner
Latest publications
Deprivation of dietary fiber in specific-pathogen-free mice promotes susceptibility to the intestinal mucosal pathogen Citrobacter rodentium.
- Eco-Immunology and Microbiome
- Experimental and Molecular Immunology
2021 Sep. Gut Microbes.13(1):1966263.
By:
- Neumann M
- Steimle A
- Grant ET
- Wolter M
- Parrish A
- Willieme S
- Brenner D
- Martens EC
- Desai MS.
High glucose enhances cytotoxic T lymphocyte-mediated cytotoxicity.
- Experimental and Molecular Immunology
2021 Jun. Front Immunol.12(2519):689337.
By:
- Zhu J
- Yang W
- Zhou X
- Zophel D
- Soriano-Baguet L
- Dolgener D
- Carlein C
- Hof C
- Zhao R
- Ye S
- Schwarz EC
- Brenner D
- Prates Roma L
- Qu B.
MondoA Drives B-ALL Malignancy through Enhanced Adaptation to Metabolic Stress.
- Experimental and Molecular Immunology
2021 Apr. Blood. Online ahead of print.
By:
- Sipol A
- Hameister E
- Xue B
- Hofstetter J
- Barenboim M
- Ollinger R
- Jain G
- Prexler C
- Rubio RA
- Baldauf MC
- Franchina DG
- Petry A
- Schmah J
- Thiel U
- Gorlach A
- Cario G
- Brenner D
- Richter G
- Grunewald TGP
- Rad R
- Wolf E
- Ruland J
- Sorensen PH
- Burdach SEG.
Editorial overview: Intrinsically tied: metabolism and immune cell function.
- Experimental and Molecular Immunology
2021 Apr. Curr Opin Biotechnol.68:iii-v. Epub 2021 Apr 17.
By:
- Hiller K
- Brenner D.
The emerging role of one-carbon metabolism in T cells.
- Experimental and Molecular Immunology
2021 Apr. Curr Opin Biotechnol.68:193-201. Epub 2021 Jan 7.
By:
- Kurniawan H
- Kobayashi T
- Brenner D.
Regulatory T cell metabolism at the intersection between autoimmune diseases and cancer.
- Experimental and Molecular Immunology
2020 Nov. Eur J Immunol.50(11):1626-1642. Epub 2020 Oct 26.
By:
- Kurniawan H
- Soriano-Baguet L
- Brenner D.
Metabolic modulation of immunity: A new Concept in cancer immunotherapy.
- Experimental and Molecular Immunology
2020 Jul. Cell Rep.32(1):107848.
By:
- Guerra L
- Bonetti L
- Brenner D.
Glutathione restricts serine metabolism to preserve Regulatory T cell function.
- Experimental and Molecular Immunology
- Allergy and Clinical Immunology
- Immune Endocrine and Epigenetics
- Cancer Metabolism Group
2020 May. Cell Metab.31(5):920-936 e7. Epub 2020 Mar 25.
By:
- Kurniawan H
- Franchina DG
- Guerra L
- Bonetti L
- Baguet LS
- Grusdat M
- Schlicker L
- Hunewald O
- Dostert C
- Merz MP
- Binsfeld C
- Duncan GS
- Farinelle S
- Nonnenmacher Y
- Haight J
- Das Gupta D
- Ewen A
- Taskesen R
- Halder R
- Chen Y
- Jager C
- Ollert M
- Wilmes P
- Vasiliou V
- Harris IS
- Knobbe-Thomsen CB
- Turner JD
- Mak TW
- Lohoff M
- Meiser J
- Hiller K
- Brenner D.
Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury.
- Experimental and Molecular Immunology
2020 Jan. Gut.69(1):133-145. Epub 2019 Aug 13.
By:
- Zhuang Y
- Xu HC
- Shinde PV
- Warfsmann J
- Vasilevska J
- Sundaram B
- Behnke K
- Huang J
- Hoell JI
- Borkhardt A
- Pfeffer K
- Taha MS
- Herebian D
- Mayatepek E
- Brenner D
- Ahmadian MR
- Keitel V
- Wieczorek D
- Haussinger D
- Pandyra AA
- Lang KS
- Lang PA.
IL-17(+) CD8(+) T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis.
- Experimental and Molecular Immunology
2019 Dec. Nat Commun.10(1):5722.
By:
- Luckel C
- Picard F
- Raifer H
- Campos Carrascosa L
- Guralnik A
- Zhang Y
- Klein M
- Bittner S
- Steffen F
- Moos S
- Marini F
- Gloury R
- Kurschus FC
- Chao YY
- Bertrams W
- Sexl V
- Schmeck B
- Bonetti L
- Grusdat M
- Lohoff M
- Zielinski CE
- Zipp F
- Kallies A
- Brenner D
- Berger M
- Bopp T
- Tackenberg B
- Huber M.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
- Experimental and Molecular Immunology
- Platform National Cytometry
2019 Oct. Eur J Immunol.49(10):1457-1973.
By:
- Cossarizza A
- Chang HD
- Radbruch A
- Acs A
- Adam D
- Adam-Klages S
- Agace WW
- Aghaeepour N
- Akdis M
- Allez M
- Almeida LN
- Alvisi G
- Anderson G
- Andra I
- Annunziato F
- Anselmo A
- Bacher P
- Baldari CT
- Bari S
- Barnaba V
- Barros-Martins J
- Battistini L
- Bauer W
- Baumgart S
- Baumgarth N
- Baumjohann D
- Baying B
- Bebawy M
- Becher B
- Beisker W
- Benes V
- Beyaert R
- Blanco A
- Boardman DA
- Bogdan C
- Borger JG
- Borsellino G
- Boulais PE
- Bradford JA
- Brenner D
- Brinkman RR
- Brooks AES
- Busch DH
- Buscher M
- Bushnell TP
- Calzetti F
- Cameron G
- Cammarata I
- Cao X
- Cardell SL
- Casola S
- Cassatella MA
- Cavani A
- Celada A
- Chatenoud L
- Chattopadhyay PK
- Chow S
- Christakou E
- Cicin-Sain L
- Clerici M
- Colombo FS
- Cook L
- Cooke A
- Cooper AM
- Corbett AJ
- Cosma A
- Cosmi L
- Coulie PG
- Cumano A
- Cvetkovic L
- Dang VD
- Dang-Heine C
- Davey MS
- Davies D
- De Biasi S
- Del Zotto G
- Dela Cruz GV
- Delacher M
- Della Bella S
- Dellabona P
- Deniz G
- Dessing M
- Di Santo JP
- Diefenbach A
- Dieli F
- Dolf A
- Dorner T
- Dress RJ
- Dudziak D
- Dustin M
- Dutertre CA
- Ebner F
- Eckle SBG
- Edinger M
- Eede P
- Ehrhardt GRA
- Eich M
- Engel P
- Engelhardt B
- Erdei A
- Esser C
- Everts B
- Evrard M
- Falk CS
- Fehniger TA
- Felipo-Benavent M
- Ferry H
- Feuerer M
- Filby A
- Filkor K
- Fillatreau S
- Follo M
- Forster I
- Foster J
- Foulds GA
- Frehse B
- Frenette PS
- Frischbutter S
- Fritzsche W
- Galbraith DW
- Gangaev A
- Garbi N
- Gaudilliere B
- Gazzinelli RT
- Geginat J
- Gerner W
- Gherardin NA
- Ghoreschi K
- Gibellini L
- Ginhoux F
- Goda K
- Godfrey DI
- Goettlinger C
- Gonzalez-Navajas JM
- Goodyear CS
- Gori A
- Grogan JL
- Grummitt D
- Grutzkau A
- Haftmann C
- Hahn J
- Hammad H
- Hammerling G
- Hansmann L
- Hansson G
- Harpur CM
- Hartmann S
- Hauser A
- Hauser AE
- Haviland DL
- Hedley D
- Hernandez DC
- Herrera G
- Herrmann M
- Hess C
- Hofer T
- Hoffmann P
- Hogquist K
- Holland T
- Hollt T
- Holmdahl R
- Hombrink P
- Houston JP
- Hoyer BF
- Huang B
- Huang FP
- Huber JE
- Huehn J
- Hundemer M
- Hunter CA
- Hwang WYK
- Iannone A
- Ingelfinger F
- Ivison SM
- Jack HM
- Jani PK
- Javega B
- Jonjic S
- Kaiser T
- Kalina T
- Kamradt T
- Kaufmann SHE
- Keller B
- Ketelaars SLC
- Khalilnezhad A
- Khan S
- Kisielow J
- Klenerman P
- Knopf J
- Koay HF
- Kobow K
- Kolls JK
- Kong WT
- Kopf M
- Korn T
- Kriegsmann K
- Kristyanto H
- Kroneis T
- Krueger A
- Kuhne J
- Kukat C
- Kunkel D
- Kunze-Schumacher H
- Kurosaki T
- Kurts C
- Kvistborg P
- Kwok I
- Landry J
- Lantz O
- Lanuti P
- LaRosa F
- Lehuen A
- LeibundGut-Landmann S
- Leipold MD
- Leung LYT
- Levings MK
- Lino AC
- Liotta F
- Litwin V
- Liu Y
- Ljunggren HG
- Lohoff M
- Lombardi G
- Lopez L
- Lopez-Botet M
- Lovett-Racke AE
- Lubberts E
- Luche H
- Ludewig B
- Lugli E
- Lunemann S
- Maecker HT
- Maggi L
- Maguire O
- Mair F
- Mair KH
- Mantovani A
- Manz RA
- Marshall AJ
- Martinez-Romero A
- Martrus G
- Marventano I
- Maslinski W
- Matarese G
- Mattioli AV
- Maueroder C
- Mazzoni A
- McCluskey J
- McGrath M
- McGuire HM
- McInnes IB
- Mei HE
- Melchers F
- Melzer S
- Mielenz D
- Miller SD
- Mills KHG
- Minderman H
- Mjosberg J
- Moore J
- Moran B
- Moretta L
- Mosmann TR
- Muller S
- Multhoff G
- Munoz LE
- Munz C
- Nakayama T
- Nasi M
- Neumann K
- Ng LG
- Niedobitek A
- Nourshargh S
- Nunez G
- O'Connor JE
- Ochel A
- Oja A
- Ordonez D
- Orfao A
- Orlowski-Oliver E
- Ouyang W
- Oxenius A
- Palankar R
- Panse I
- Pattanapanyasat K
- Paulsen M
- Pavlinic D
- Penter L
- Peterson P
- Peth C
- Petriz J
- Piancone F
- Pickl WF
- Piconese S
- Pinti M
- Pockley AG
- Podolska MJ
- Poon Z
- Pracht K
- Prinz I
- Pucillo CEM
- Quataert SA
- Quatrini L
- Quinn KM
- Radbruch H
- Radstake T
- Rahmig S
- Rahn HP
- Rajwa B
- Ravichandran G
- Raz Y
- Rebhahn JA
- Recktenwald D
- Reimer D
- Reis e Sousa C
- Remmerswaal EBM
- Richter L
- Rico LG
- Riddell A
- Rieger AM
- Robinson JP
- Romagnani C
- Rubartelli A
- Ruland J
- Saalmuller A
- Saeys Y
- Saito T
- Sakaguchi S
- Sala-de-Oyanguren F
- Samstag Y
- Sanderson S
- Sandrock I
- Santoni A
- Sanz RB
- Saresella M
- Sautes-Fridman C
- Sawitzki B
- Schadt L
- Scheffold A
- Scherer HU
- Schiemann M
- Schildberg FA
- Schimisky E
- Schlitzer A
- Schlosser J
- Schmid S
- Schmitt S
- Schober K
- Schraivogel D
- Schuh W
- Schuler T
- Schulte R
- Schulz AR
- Schulz SR
- Scotta C
- Scott-Algara D
- Sester DP
- Shankey TV
- Silva-Santos B
- Simon AK
- Sitnik KM
- Sozzani S
- Speiser DE
- Spidlen J
- Stahlberg A
- Stall AM
- Stanley N
- Stark R
- Stehle C
- Steinmetz T
- Stockinger H
- Takahama Y
- Takeda K
- Tan L
- Tarnok A
- Tiegs G
- Toldi G
- Tornack J
- Traggiai E
- Trebak M
- Tree TIM
- Trotter J
- Trowsdale J
- Tsoumakidou M
- Ulrich H
- Urbanczyk S
- van de Veen W
- van den Broek M
- van der Pol E
- Van Gassen S
- Van Isterdael G
- van Lier RAW
- Veldhoen M
- Vento-Asturias S
- Vieira P
- Voehringer D
- Volk HD
- von Borstel A
- von Volkmann K
- Waisman A
- Walker RV
- Wallace PK
- Wang SA
- Wang XM
- Ward MD
- Ward-Hartstonge KA
- Warnatz K
- Warnes G
- Warth S
- Waskow C
- Watson JV
- Watzl C
- Wegener L
- Weisenburger T
- Wiedemann A
- Wienands J
- Wilharm A
- Wilkinson RJ
- Willimsky G
- Wing JB
- Winkelmann R
- Winkler TH
- Wirz OF
- Wong A
- Wurst P
- Yang JHM
- Yang J
- Yazdanbakhsh M
- Yu L
- Yue A
- Zhang H
- Zhao Y
- Ziegler SM
- Zielinski C
- Zimmermann J
- Zychlinsky A.
Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery.
- Experimental and Molecular Immunology
2019 May. Eur J Immunol.49(5):770-781. Epub 2019 Feb 20.
By:
- Wilson AS
- Law HD
- Knobbe-Thomsen CB
- Kearney CJ
- Oliaro J
- Binsfeld C
- Burgio G
- Starrs L
- Brenner D
- Randall KL
- Brustle A.
Choline acetyltransferase-expressing T cells are required to control chronic viral infection.
- Experimental and Molecular Immunology
2019 Feb. Science.363(6427):639-644.
By:
- Cox MA
- Duncan GS
- Lin GHY
- Steinberg BE
- Yu LX
- Brenner D
- Buckler LN
- Elia AJ
- Wakeham AC
- Nieman B
- Dominguez-Brauer C
- Elford AR
- Gill KT
- Kubli SP
- Haight J
- Berger T
- Ohashi PS
- Tracey KJ
- Olofsson PS
- Mak TW.
The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond.
- Experimental and Molecular Immunology
2019 Jan. Physiol Rev.99(1):115-160.
By:
- Dostert C
- Grusdat M
- Letellier E
- Brenner D.
Reactive Oxygen species: Involvement in T cell signaling and metabolism.
- Experimental and Molecular Immunology
2018 Jun. Trends Immunol.39(6):489-502. Epub 2018 Feb 13.
By:
- Franchina DG
- Dostert C
- Brenner D.
Tumor Necrosis Factor-Mediated Survival of CD169(+) Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.
- Experimental and Molecular Immunology
2018 Feb. J Virol.92(3).
By:
- Shinde PV
- Xu HC
- Maney SK
- Kloetgen A
- Namineni S
- Zhuang Y
- Honke N
- Shaabani N
- Bellora N
- Doerrenberg M
- Trilling M
- Pozdeev VI
- van Rooijen N
- Scheu S
- Pfeffer K
- Crocker PR
- Tanaka M
- Duggimpudi S
- Knolle P
- Heikenwalder M
- Ruland J
- Mak TW
- Brenner D
- Pandyra AA
- Hoell JI
- Borkhardt A
- Haussinger D
- Lang KS
- Lang PA.
Survival of the fittest: Cancer challenges T cell metabolism.
- Experimental and Molecular Immunology
- Immune Systems Biology
2018 Jan. Cancer Lett.412:216-223. Epub 2017 Oct 24.
By:
- Franchina DG
- He F
- Brenner D.
MALT1 is an intrinsic regulator of regulatory T cells.
- Experimental and Molecular Immunology
2017 Jul. Cell Death Differ.24(7):1214-1223. Epub 2015 Sep 25.
By:
- Brustle A
- Brenner D
- Knobbe-Thomsen CB
- Cox M
- Lang PA
- Lang KS
- Mak TW.
Glutathione primes T cell metabolism for inflammation.
- Experimental and Molecular Immunology
- Allergy and Clinical Immunology
2017 Apr. Immunity.46(4):675-689.
By:
- Mak TW
- Grusdat M
- Duncan GS
- Dostert C
- Nonnenmacher Y
- Cox M
- Binsfeld C
- Hao Z
- Brustle A
- Itsumi M
- Jager C
- Chen Y
- Pinkenburg O
- Camara B
- Ollert M
- Bindslev-Jensen C
- Vasiliou V
- Gorrini C
- Lang PA
- Lohoff M
- Harris IS
- Hiller K
- Brenner D.
K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.
- Experimental and Molecular Immunology
2017 Jan. Nat Commun.8:14003.
By:
- Hao Z
- Sheng Y
- Duncan GS
- Li WY
- Dominguez C
- Sylvester J
- Su YW
- Lin GH
- Snow BE
- Brenner D
- You-Ten A
- Haight J
- Inoue S
- Wakeham A
- Elford A
- Hamilton S
- Liang Y
- Zuniga-Pflucker JC
- He HH
- Ohashi PS
- Mak TW.