Latest publications
A DNA repair and cell-cycle gene expression signature in primary and recurrent glioblastoma: prognostic value and clinical implications.
- DNA Repair and Chemoresistance
- Computational Biomedicine
- NORLUX Neuro-Oncology Laboratory
2019 Mar. Cancer Res.79(6):1226-1238. Epub 2019 Jan 23.
Artificial intelligence for precision oncology: beyond patient stratification.
- Computational Biomedicine
2019 Feb. NPJ Precis Oncol.3:6.
RNAi/CRISPR Screens: from a Pool to a Valid Hit.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- DNA Repair and Chemoresistance
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
2018 Nov. EMBO Rep.19(11). Epub 2018 Sep 11.
Cytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets.
- Computational Biomedicine
2018 Nov. J Leukoc Biol.104(5):987-1002. Epub 2018 Aug 26.
Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer.
- Proteomics of Cellular Signaling
- Competence Center for Methodology and Statistics
- Computational Biomedicine
- Clinical and Epidemiological Investigation Center
- Integrated BioBank of Luxembourg
2018 Aug. Br J Cancer.119(5):580-590. Epub 2018 Aug 6.
Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach.
- Computational Biomedicine
2018 Jun. Biol Direct.13(1):12.
Inhibition of HIF1alpha-dependent upregulation of Phospho-l-Plastin resensitizes multiple myeloma cells to frontline therapy.
- Tumor Immunotherapy and Microenvironment
- Computational Biomedicine
- Laboratory of Oncolytic-Virus-Immuno-Therapeutics
2018 May. Int J Mol Sci.19(6):1551.
CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival.
- Luxembourg Center of Neuropathology
- Computational Biomedicine
2018 Mar. Acta Neuropathol Commun.6(1):18.
Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer.
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
2018 Mar. Int J Cancer.142(5):1010-1021. Epub 2017 Oct 17.
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.
- Tumor Immunotherapy and Microenvironment
- Computational Biomedicine
2018 Feb. OncoImmunology.7(4):e1345415.
Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.
- NORLUX Neuro-Oncology Laboratory
- Translational Radiomics
- Computational Biomedicine
2017 Dec. EMBO Mol Med.9(12):1681-1695.
Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
- Tumor Immunotherapy and Microenvironment
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
Computational models for predicting drug responses in cancer research.
- Computational Biomedicine
2017 Sep. Brief Bioinform.18(5):820-829.
Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.
- Luxembourg Center of Neuropathology
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
- NORLUX Neuro-Oncology Laboratory
2017 Aug. Int J Oncol.51(2):702-714. Epub 2017 Jun 21.
Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
2017 Aug. J Pathol.242(4):421-434. Epub 2017 Jul 5.
Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
2017 Jul. Cancer Discov.7(7):716-735. Epub 2017 Apr 17.
RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples.
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
- Proteomics of Cellular Signaling
2017 Jun. BMC Genomics.18(1):443.
The angiogenic switch leads to a metabolic shift in human glioblastoma.
- NORLUX Neuro-Oncology Laboratory
- Computational Biomedicine
- Platform LUXGEN - Micro-Array
2017 Mar. Neuro Oncol.19(3):383-393.
LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.
- Computational Biomedicine
2016 Sep. EMBO Mol Med.8(9):1052-64.