Guy Berchem
Latest publications
In vitro sensitivity to venetoclax and microenvironment protection in hairy cell leukemia.
- Tumor Stroma Interactions
2021 Jul. Front Oncol.11:598319.
Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy.
- Tumor Immunotherapy and Microenvironment
2021 Jul. Oncogene.40(28):4725-4735. Epub 2021 Jun 21.
Intrinsic resistance of chronic lymphocytic leukemia cells to NK cell- mediated lysis can be overcome in vitro by pharmacological inhibition of Cdc42-induced actin cytoskeleton remodeling.
- Cytoskeleton and Cancer Progression
- Tumor Stroma Interactions
2021 May. Front Immunol.12:619069.
Systematic review and network meta-analysis of the efficacy of existing treatments for patients with recurrent glioblastoma.
- Competence Center for Methodology and Statistics
- Clinical and Epidemiological Investigation Center
- Public Health Research
2021 Apr. Neurooncol Adv.3(1):vdab052.
Epithelial to mesenchymal transition regulates surface PD-L1 via CMTM6 and CMTM7 induction in breast cancer.
- Tumor Immunotherapy and Microenvironment
2021 Mar. Cancers.13(5):1165.
CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6.
- Immuno-Pharmacology and Interactomics
- Tumor Immunotherapy and Microenvironment
- Allergy and Clinical Immunology
- Personalized Therapy Discovery
2021 Mar. Cancers.13(5):1054.
Targeting cytoprotective autophagy to enhance anticancer therapies.
- Tumor Immunotherapy and Microenvironment
2021 Feb. Front Oncol.11:626309.
Lessons learned from COVID-19 lockdown for cancer care: a nationwide survey of oncologists in Luxembourg.
- Public Health Expertise
- Public Health Research
2021 Jan. Bull Soc Sci Med Grand Duche Luxemb.(2):39-61.
Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34.
- Tumor Immunotherapy and Microenvironment
2020 Nov. Autophagy.(11):2110-2111. Epub 2020 Sep 5.
Firing up the cold tumors by targeting Vps34.
- Tumor Immunotherapy and Microenvironment
2020 Aug. OncoImmunology.9(1):1809936.
Identification of a blood-based protein biomarker panel for lung cancer detection.
- Personalized Therapy Discovery
- Competence Center for Methodology and Statistics
- Multiomics Data Science
- Quantitative Biology Unit
- NORLUX Neuro-Oncology Laboratory
2020 Jun. Cancers.12(6):E1629.
The emerging impact of autophagy on the antitumor immune response. In Autophagy in immune response: Impact on cancer immunotherapy. 1st ed. (Book Chapter)
- Tumor Immunotherapy and Microenvironment
2020 May. Chouaib S, ed. London: Academic Press, 2020. p.109-117. (Sensitizing Agent-Canc Resistant-Cell Mediated Immtherap, Vol.1). ISBN 978-0-12-819609-0.
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy.
- Tumor Immunotherapy and Microenvironment
2020 May. Sci Adv.6(18):eaax7881.
Improving cancer immunotherapy by targeting the hypoxic tumor microenvironment: new opportunities and challenges.
- Tumor Immunotherapy and Microenvironment
2019 Sep. Cells.8(9).
Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints.
- Tumor Immunotherapy and Microenvironment
2019 Aug. Cancer Lett.458:13-20. Epub 2019 May 25.
Involvement of HPV infection in the release of macrophage migration Inhibitory factor in head and neck squamous cell carcinoma.
- Tumor Immunotherapy and Microenvironment
2019 Jan. J Clin Med.8(1).
Actin cytoskeleton remodeling drives breast cancer cell escape from natural killer-mediated cytotoxicity.
- Cytoskeleton and Cancer Progression
- Platform National Cytometry
- NORLUX Neuro-Oncology Laboratory
- Tumor Immunotherapy and Microenvironment
2018 Oct. Cancer Res.78(19):5631-5643. Epub 2018 Aug 13.
Driving cytotoxic natural killer cells into melanoma: If CCL5 plays the music, autophagy calls the shots.
- Tumor Immunotherapy and Microenvironment
- Immuno-Pharmacology and Interactomics
- Allergy and Clinical Immunology
2018 Sep. Crit Rev Oncog.23(5-6):321-332.
Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer.
- Proteomics of Cellular Signaling
- Competence Center for Methodology and Statistics
- Computational Biomedicine
- Clinical and Epidemiological Investigation Center
- Integrated BioBank of Luxembourg
2018 Aug. Br J Cancer.119(5):580-590. Epub 2018 Aug 6.
Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2.
- Cytoskeleton and Cancer Progression
- Tumor Immunotherapy and Microenvironment
2018 Jul. Sci Rep.8(1):10191.