Fred Fack

Latest publications

Cystathionine-gamma-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas.

  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
  • Quantitative Biology Unit
  • Cancer Metabolism Group
April 09, 2021
2021 Apr. Neurooncol Adv.3(1):vdab057.
By:
  • Cano-Galiano A
  • Oudin A
  • Fack F
  • Allega MF
  • Sumpton D
  • Martinez-Garcia E
  • Dittmar G
  • Hau AC
  • De Falco A
  • Herold-Mende C
  • Bjerkvig R
  • Meiser J
  • Tardito S
  • Niclou SP.
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Investigation of IDH-mutant Gliomas Metabolism by Mass Spectrometry Imaging (Application Note #MSI-16)

  • NORLUX Neuro-Oncology Laboratory
June 25, 2018
2018 Jun. Imabiotech, 2018. 4 p.
By:
  • Hochart G
  • Fack F
  • Tardito S
  • Stauber J
  • Fontaine E
  • Niclou S
  • Stauber J.
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Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
December 01, 2017
2017 Dec. EMBO Mol Med.9(12):1681-1695.
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.
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Targeted proteomics to assess the response to anti-angiogenic treatment in human glioblastoma (GBM).

  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
February 01, 2016
2016 Feb. Mol Cell Proteomics.15(2):481-92. Epub 2015 Aug 4.
By:
  • Demeure K
  • Fack F
  • Duriez E
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Bougnaud S
  • Bjerkvig R
  • Domon B
  • Niclou SP.
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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
December 01, 2015
2015 Dec. Nat Cell Biol.17(12):1556-68. Epub 2015 Nov 23.
By:
  • Tardito S
  • Oudin A
  • Ahmed SU
  • Fack F
  • Keunen O
  • Zheng L
  • Miletic H
  • Sakariassen PO
  • Weinstock A
  • Wagner A
  • Lindsay SL
  • Hock AK
  • Barnett SC
  • Ruppin E
  • Morkve SH
  • Lund-Johansen M
  • Chalmers AJ
  • Bjerkvig R
  • Niclou SP
  • Gottlieb E.
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Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
January 01, 2015
2015 Jan. Acta Neuropathol.129(1):115-31. Epub 2014 Oct 17.
By:
  • Fack F
  • Espedal H
  • Keunen O
  • Golebiewska A
  • Obad N
  • Harter PN
  • Mittelbronn M
  • Bahr O
  • Weyerbrock A
  • Stuhr L
  • Miletic H
  • Sakariassen PO
  • Stieber D
  • Rygh CB
  • Lund-Johansen M
  • Zheng L
  • Gottlieb E
  • Niclou SP
  • Bjerkvig R.
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Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture.

  • NORLUX Neuro-Oncology Laboratory
July 11, 2014
2014 Jul. Proteome Sci.12:39.
By:
  • Rajcevic U
  • Knol JC
  • Piersma S
  • Bougnaud S
  • Fack F
  • Sundlisaeter E
  • Sondenaa K
  • Myklebust R
  • Pham TV
  • Niclou SP
  • Jimenez CR.
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The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

  • NORLUX Neuro-Oncology Laboratory
September 01, 2013
2013 Sep. Neuro Oncol.15(9):1200-11. Epub 2013 May 30.
By:
  • Johansson M
  • Oudin A
  • Tiemann K
  • Bernard A
  • Golebiewska A
  • Keunen O
  • Fack F
  • Stieber D
  • Wang B
  • Hedman H
  • Niclou SP.
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Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

  • Integrated BioBank of Luxembourg
  • NORLUX Neuro-Oncology Laboratory
June 01, 2013
2013 Jun. Biopreserv Biobank.11(3):161-5.
By:
  • Kofanova OA
  • Fack F
  • Niclou SP
  • Betsou F.
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Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

  • NORLUX Neuro-Oncology Laboratory
May 29, 2013
2013 May. Acta Neuropathol Commun.1:18.
By:
  • Navis AC
  • Niclou SP
  • Fack F
  • Stieber D
  • van Lith S
  • Verrijp K
  • Wright A
  • Stauber J
  • Tops B
  • Otte-Holler I.
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Identification of differentially expressed proteins in curcumin-treated prostate cancer cell lines.

  • Clinical and Applied Virology
June 01, 2012
2012 Jun. OMICS.16(6):289-300. Epub 2012 Apr 4.
By:
  • Teiten MH
  • Gaigneaux A
  • Chateauvieux S
  • Billing AM
  • Planchon S
  • Fack F
  • Renaut J
  • Mack F
  • Muller CP
  • Dicato M
  • Diederich M.
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Atrazine and PCB 153 and their effects on the proteome of subcellular fractions of human MCF-7 cells.

  • Clinical and Applied Virology
June 01, 2012
2012 Jun. Biochim Biophys Acta-Proteins Proteomics 1824(6):833-41. Epub 2012 Apr 16.
By:
  • Lasserre JP
  • Fack F
  • Serchi T
  • Revets D
  • Planchon S
  • Renaut J
  • Hoffmann L
  • Gutleb AC
  • Muller CP
  • Bohn T.
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Detection of differentially modified pathogen proteins by western blot after 2D Gel electrophoresis and identification by MALDI-TOF/TOF. In BSL3 and BSL4 Agents: Proteomics, Glycomics, and Antigenicity. (Book Chapter)

  • NORLUX Neuro-Oncology Laboratory
  • Platform National Cytometry
  • Clinical and Applied Virology
September 30, 2011
2011 Sep. Stulik J, Toman R, Butaye P and Ulrich RG, eds. Weinheim: Wiley-VCH Verlag, 2011. p.131-138. ISBN 9783527327805.
By:
  • Fack F
  • Kessler JR
  • Pirrotte P
  • Kremer JR
  • Revets D
  • Ammerlaan W
  • Muller CP.
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Cortisol is a potent modulator of lipopolysaccharide-induced interferon signaling in macrophages.

  • Clinical and Applied Virology
June 01, 2011
2011 Jun. Innate Immun.17(3):302-20. Epub 2010 May 25.
By:
  • Billing AM
  • Fack F
  • Turner JD
  • Muller CP.
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Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
March 01, 2011
2011 Mar. Proc Natl Acad Sci U S A.108(9):3749-54. Epub 2011 Feb 14.
By:
  • Keunen O
  • Johansson M
  • Oudin A
  • Sanzey M
  • Rahim SA
  • Fack F
  • Thorsen F
  • Taxt T
  • Bartos M
  • Jirik R
  • Miletic H
  • Wang J
  • Stieber D
  • Stuhr L
  • Moen I
  • Rygh CB
  • Bjerkvig R
  • Niclou SP.
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Extensive phosphorylation flanking the C-terminal functional domains of the measles virus nucleoprotein.

  • Clinical and Applied Virology
November 05, 2010
2010 Nov. J Proteome Res.9(11):5598-609. Epub 2010 Oct 6.
By:
  • Prodhomme EJ
  • Fack F
  • Revets D
  • Pirrotte P
  • Kremer JR
  • Muller CP.
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Glioma proteomics: status and perspectives.

  • NORLUX Neuro-Oncology Laboratory
September 10, 2010
2010 Sep. J Proteomics.73(10):1823-38. Epub 2010 Mar 20.
By:
  • Niclou SP
  • Fack F
  • Rajcevic U.
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