Anna Golebiewska

Latest publications

Cancer cell heterogeneity and plasticity: A paradigm shift in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
December 21, 2021
2021 Dec. Neuro Oncol. Online ahead of print.
By:
  • Yabo YA
  • Niclou SP
  • Golebiewska A.
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Turning strength into weakness: protein degradation and autophagy as therapeutic targets in Glioblastoma?

  • NORLUX Neuro-Oncology Laboratory
July 01, 2021
2021 Jul. Neuro Oncol.23(7):1041-1043.
By:
  • Niclou SP
  • Golebiewska A.
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Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry.

  • Laboratory of Oncolytic-Virus-Immuno-Therapeutics
  • NORLUX Neuro-Oncology Laboratory
June 22, 2021
2021 Jun. Nat Commun.12(1):3834.
By:
  • Kulkarni A
  • Ferreira T
  • Bretscher C
  • Grewenig A
  • El-Andaloussi N
  • Bonifati S
  • Marttila T
  • Palissot V
  • Hossain JA
  • Azuaje F
  • Miletic H
  • Ystaas LAR
  • Golebiewska A
  • Niclou SP
  • Roeth R
  • Niesler B
  • Weiss A
  • Brino L
  • Marchini A.
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Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors.

  • NORLUX Neuro-Oncology Laboratory
  • Neuro-Immunology Group
  • Translational Radiomics
June 18, 2021
2021 Jun. STAR Protoc.2(2):100534.
By:
  • Oudin A
  • Baus V
  • Barthelemy V
  • Fabian C
  • Klein E
  • Dieterle M
  • Wantz M
  • Hau AC
  • Dording C
  • Bernard A
  • Michelucci A
  • Yabo YA
  • Kanli G
  • Keunen O
  • Bjerkvig R
  • Niclou SP
  • Golebiewska A.
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Hub genes in a pan-cancer co-expression network show potential for predicting drug responses.

  • Computational Biomedicine
  • NORLUX Neuro-Oncology Laboratory
  • Proteomics of Cellular Signaling
May 24, 2021
2021 May. F1000Res.7:1906.
By:
  • Azuaje F
  • Kaoma T
  • Jeanty C
  • Nazarov PV
  • Muller A
  • Kim SY
  • Dittmar G
  • Golebiewska A
  • Niclou SP.
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.

  • NORLUX Neuro-Oncology Laboratory
January 01, 2021
2021 Jan. Nat Genet.53(1):86-99. Epub 2021 Jan 7.
By:
  • Woo XY
  • Giordano J
  • Srivastava A
  • Zhao ZM
  • Lloyd MW
  • de Bruijn R
  • Suh YS
  • Patidar R
  • Chen L
  • Scherer S
  • Bailey MH
  • Yang CH
  • Cortes-Sanchez E
  • Xi Y
  • Wang J
  • Wickramasinghe J
  • Kossenkov AV
  • Rebecca VW
  • Sun H
  • Mashl RJ
  • Davies SR
  • Jeon R
  • Frech C
  • Randjelovic J
  • Rosains J
  • Galimi F
  • Bertotti A
  • Lafferty A
  • O'Farrell AC
  • Modave E
  • Lambrechts D
  • Ter Brugge P
  • Serra V
  • Marangoni E
  • El Botty R
  • Kim H
  • Kim JI
  • Yang HK
  • Lee C
  • Dean DA
  • 2nd
  • Davis-Dusenbery B
  • Evrard YA
  • Doroshow JH
  • Welm AL
  • Welm BE
  • Lewis MT
  • Fang B
  • Roth JA
  • Meric-Bernstam F
  • Herlyn M
  • Davies MA
  • Ding L
  • Li S
  • Govindan R
  • Isella C
  • Moscow JA
  • Trusolino L
  • Byrne AT
  • Jonkers J
  • Bult CJ
  • Medico E
  • Chuang JH
  • Pdxnet Consortium
  • EurOPDX Consortium (Golebiewska A. and Niclou S.P. as collaborators for Luxembourg).
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).

  • NORLUX Neuro-Oncology Laboratory
  • Tumor Immunotherapy and Microenvironment
  • Digital Medicine
January 01, 2021
2021 Jan. Autophagy.17(1):1-382. Epub 2021 Feb 8.
By:
  • Klionsky DJ
  • Abdel-Aziz AK
  • Abdelfatah S
  • Abdellatif M
  • Abdoli A
  • et al
  • Golebiewska A. (Author for LIH)
  • Janji B. (Author for LIH)
  • Klucken J. (Author for LIH).
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AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.

  • NORLUX Neuro-Oncology Laboratory
  • Multiomics Data Science
  • Quantitative Biology Unit
  • Proteomics of Cellular Signaling
December 11, 2020
2020 Dec. Nat Commun.11(1):6366.
By:
  • Schuster A
  • Klein E
  • Neirinckx V
  • Knudsen AM
  • Fabian C
  • Hau AC
  • Dieterle M
  • Oudin A
  • Nazarov PV
  • Golebiewska A
  • Muller A
  • Perez-Hernandez D
  • Rodius S
  • Dittmar G
  • Bjerkvig R
  • Herold-Mende C
  • Klink B
  • Kristensen BW
  • Niclou SP.
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Glioblastoma organoids: Pre-clinical applications and challenges in the context of immunotherapy.

  • NORLUX Neuro-Oncology Laboratory
December 08, 2020
2020 Dec. Front Oncol.10:604121.
By:
  • Klein E
  • Hau AC
  • Oudin A
  • Golebiewska A
  • Niclou SP.
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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Neuro-Immunology Group
  • Computational Biomedicine
  • Multiomics Data Science
  • Luxembourg Center of Neuropathology
  • Personalized Therapy Discovery
December 01, 2020
2020 Dec. Acta Neuropathol.140(6):919-949. Epub 2020 Oct 3.
By:
  • Golebiewska A
  • Hau AC
  • Oudin A
  • Stieber D
  • Yabo YA
  • Baus V
  • Barthelemy V
  • Klein E
  • Bougnaud S
  • Keunen O
  • Wantz M
  • Michelucci A
  • Neirinckx V
  • Muller A
  • Kaoma T
  • Nazarov PV
  • Azuaje F
  • De Falco A
  • Flies B
  • Richart L
  • Poovathingal S
  • Arns T
  • Grzyb K
  • Mock A
  • Herold-Mende C
  • Steino A
  • Brown D
  • May P
  • Miletic H
  • Malta TM
  • Noushmehr H
  • Kwon YJ
  • Jahn W
  • Klink B
  • Tanner G
  • Stead LF
  • Mittelbronn M
  • Skupin A
  • Hertel F
  • Bjerkvig R
  • Niclou SP.
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New hints towards a precision medicine strategy for IDH wild-type glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
December 01, 2020
2020 Dec. Ann Oncol.31(12):1679-1692. Epub 2020 Sep 9.
By:
  • White K
  • Connor K
  • Clerkin J
  • Murphy BM
  • Salvucci M
  • O'Farrell AC
  • Rehm M
  • O'Brien D
  • Prehn JHM
  • Niclou SP
  • Lamfers MLM
  • Verreault M
  • Idbaih A
  • Verhaak R
  • Golebiewska A
  • Byrne AT.
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Temozolomide-induced RNA interactome uncovers novel lncRNA regulatory loops in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Quantitative Biology Unit
  • DNA Repair and Chemoresistance
September 10, 2020
2020 Sep. Cancers.12(9).
By:
  • Fritah S
  • Muller A
  • Jiang W
  • Mitra R
  • Sarmini M
  • Dieterle M
  • Golebiewska A
  • Ye T
  • Van Dyck E
  • Herold-Mende C
  • Zhao Z
  • Azuaje F
  • Niclou SP.
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Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.

  • Luxembourg Center of Neuropathology
  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
July 01, 2019
2019 Jul. Brain Pathol.29(4):513-529. Epub 2019 Jan 15.
By:
  • Zeiner PS
  • Preusse C
  • Golebiewska A
  • Zinke J
  • Iriondo A
  • Muller A
  • Kaoma T
  • Filipski K
  • Muller-Eschner M
  • Bernatz S
  • Blank AE
  • Baumgarten P
  • Ilina E
  • Grote A
  • Hansmann ML
  • Verhoff MA
  • Franz K
  • Feuerhake F
  • Steinbach JP
  • Wischhusen J
  • Stenzel W
  • Niclou SP
  • Harter PN
  • Mittelbronn M.
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Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • Competence Center for Methodology and Statistics
  • Platform National Cytometry
April 16, 2019
2019 Apr. Nat Commun.10(1):1787.
By:
  • Dirkse A
  • Golebiewska A
  • Buder T
  • Nazarov PV
  • Muller A
  • Poovathingal S
  • Brons NHC
  • Leite S
  • Sauvageot N
  • Sarkisjan D
  • Seyfrid M
  • Fritah S
  • Stieber D
  • Michelucci A
  • Hertel F
  • Herold-Mende C
  • Azuaje F
  • Skupin A
  • Bjerkvig R
  • Deutsch A
  • Voss-Bohme A
  • Niclou SP.
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RNAi/CRISPR Screens: from a Pool to a Valid Hit.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • DNA Repair and Chemoresistance
January 01, 2019
2019 Jan. Trends Biotechnol.37(1):38-55. Epub 2018 Aug 31.
By:
  • Schuster A
  • Erasimus H
  • Fritah S
  • Nazarov PV
  • van Dyck E
  • Niclou SP
  • Golebiewska A.
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Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
November 01, 2018
2018 Nov. EMBO Rep.19(11). Epub 2018 Sep 11.
By:
  • Sousa C
  • Golebiewska A
  • Poovathingal SK
  • Kaoma T
  • Pires-Afonso Y
  • Martina S
  • Coowar D
  • Azuaje F
  • Skupin A
  • Balling R
  • Biber K
  • Niclou SP
  • Michelucci A.
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EGFL7 enhances surface expression of integrin alpha5beta1 to promote angiogenesis in malignant brain tumors.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Luxembourg Center of Neuropathology
September 01, 2018
2018 Sep. EMBO Mol Med.10(9).
By:
  • Dudvarski Stankovic N
  • Bicker F
  • Keller S
  • Jones DT
  • Harter PN
  • Kienzle A
  • Gillmann C
  • Arnold P
  • Golebiewska A
  • Keunen O
  • Giese A
  • von Deimling A
  • Bauerle T
  • Niclou SP
  • Mittelbronn M
  • Ye W
  • Pfister SM
  • Schmidt MHH.
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Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
December 01, 2017
2017 Dec. EMBO Mol Med.9(12):1681-1695.
By:
  • Fack F
  • Tardito S
  • Hochart G
  • Oudin A
  • Zheng L
  • Fritah S
  • Golebiewska A
  • Nazarov PV
  • Bernard A
  • Hau AC
  • Keunen O
  • Leenders W
  • Lund-Johansen M
  • Stauber J
  • Gottlieb E
  • Bjerkvig R
  • Niclou SP.
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Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

  • NORLUX Neuro-Oncology Laboratory
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Tumor Immunotherapy and Microenvironment
September 05, 2017
2017 Sep. Br J Cancer.117(6):813-825. Epub 2017 Aug 10.
By:
  • Abdul Rahim SA
  • Dirkse A
  • Oudin A
  • Schuster A
  • Bohler J
  • Barthelemy V
  • Muller A
  • Vallar L
  • Janji B
  • Golebiewska A
  • Niclou SP.
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Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.

  • NORLUX Neuro-Oncology Laboratory
  • Translational Radiomics
  • Computational Biomedicine
  • Platform LUXGEN - Micro-Array
  • Platform National Cytometry
May 31, 2016
2016 May. Oncotarget.7(22):31955-71.
By:
  • Bougnaud S
  • Golebiewska A
  • Oudin A
  • Keunen O
  • Harter PN
  • Mader L
  • Azuaje F
  • Fritah S
  • Stieber D
  • Kaoma T
  • Vallar L
  • Brons NH
  • Daubon T
  • Miletic H
  • Sundstrom T
  • Herold-Mende C
  • Mittelbronn M
  • Bjerkvig R
  • Niclou SP.
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