Biospecimen science of blood for Peripheral Blood Mononuclear Cell (PBMC) functional applications.

  • Integrated BioBank of Luxembourg
June 01, 2019 By:
  • Betsou F
  • Gaignaux A
  • Ammerlaan W
  • Norris PJ
  • Stone M.

Peripheral blood mononuclear cells (PBMCs) are used in a wide variety of preclinical assays. Preanalytical variations can have a devastating impact on the results. In this review, we list critical preanalytical factors for PBMC-based assays to develop awareness and orientation to the types of sample preparation and storage that one may consider employing.

2019 Jun. Curr Pathobiol Rep.7(2):17-27.
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